POLIVY (polatuzumab vedotin-piiq)


OFFICE ADMINISTRATION


Indications for Prior Authorization:
  • Indicated in combination with bendamustine and a rituximab product for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) after at least 2 prior therapies.


Patients must meet the following criteria for the indication(s) above:
  • Patient is 18 years of age or older, AND

  • Diagnosis of relapsed or refractory diffuse large B-cell lymphoma or high-grade B-cell lymphoma, AND

  • Prescribed by or in consultation with an oncologist, AND

  • Patient has received at least two prior chemotherapy regimens (e.g. RCHOP, HSCT, CAR T, RCEPP, GemOx), AND

  • Polivy™ will be used in combination with bendamustine and a rituximab product (e.g. Rituxan, Truxima)


Dosing:
  • 1.8 mg/kg IV once every 21 days for 6 cycles (in combination with bendamustine and rituximab)

Approval:
  • 6 months

Last review date: October 15, 2019