TALZENNA (talazoparib)
SELF ADMINISTRATION - ORAL
Indications for Prior Authorizations:
- Indicated in adult patients with deleterious or suspected deleterious germline BReast CAncer susceptibility gene (BRCA)-mutated (gBRCAm) human epidermal growth factor receptor 2 (HER2)-negative locally-advanced or metastatic breast cancer.
Must meet the following criteria for coverage:
- Patient is of 18 years of age or older, AND
- Prescribed by or in consultation with an oncologist, AND
- Patient has locally-advanced or metastatic breast cancer, AND
- Patient has germline BRCA mutation-positive disease, AND
- Patient has human epidermal growth factor receptor 2 (HER2)-negative breast cancer
Dosing:
- 1 mg taken orally once daily
- 0.25 mg capsule is available for dose reduction
Approval:
1 year
Last review date: December 4, 2019