Ophthalmic Prostaglandins

Indications for Prior Authorization

Xelpros (latanoprost)
  • For diagnosis of Open-angle glaucoma
    Indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma.

  • For diagnosis of Ocular hypertension
    Indicated for the reduction of elevated intraocular pressure (IOP) in patients with ocular hypertension.

Vyzulta (latanoprostene bunod)
  • For diagnosis of Open-angle glaucoma
    Indicated for the reduction of intraocular pressure in patients with open-angle glaucoma.

  • For diagnosis of Ocular hypertension
    Indicated for the reduction of intraocular pressure in patients with ocular hypertension.

Iyuzeh (latanoprost ophthalmic solution)
  • For diagnosis of Open-angle glaucoma, Ocular hypertension
    Indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

Criteria

Iyuzeh, Xelpros, Vyzulta

Step Therapy

Length of Approval: 12 Month(s)

  • Requested drug is being used for a Food and Drug Administration (FDA)-approved indication
  • AND
  • Trial and failure (of a minimum 25 days supply), contraindication, or intolerance to all of the following:
    • Generic latanoprost
    • Lumigan
    • Generic travoprost
P & T Revisions

2024-01-05, 2023-11-02, 2023-01-20, 2022-01-27, 2021-01-19, 2020-09-30, 2020-03-02

  1. Xelpros Prescribing Information. Sun Pharmaceutical Industries, Inc. Cranbury, NJ. February 2021.
  2. Vyzulta Prescribing Information. Bausch & Lomb Incorporated. Bridgewater, NJ. May 2019.
  3. Iyuzeh Prescribing Information. Thea Pharma Inc. Waltham, MA. December 2022.

  • 2024-01-05: 2024 Annual Review.
  • 2023-11-02: Added Iyuzeh as target to guideline.
  • 2023-01-20: 2023 Annual Review
  • 2022-01-27: Annual Review
  • 2021-01-19: Annual Review: updated minimum trial and failure duration verbiage
  • 2020-09-30: Program Update: added lookback period and removed Brand Travatan Z as an option on the ST program
  • 2020-03-02: Add travoprost in ST

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